Subject(s)
Humans , Cat-Scratch Disease/diagnosis , Coccidioidomycosis/diagnosis , Histoplasmosis/diagnosis , Leishmaniasis/diagnosis , Lymphadenitis/etiology , Mycobacterium Infections, Nontuberculous/diagnosis , Mycobacterium Infections/diagnosis , Nocardia Infections/diagnosis , Sporotrichosis/diagnosis , Tularemia/diagnosis , Fungi/pathogenicity , Lymphadenitis/pathology , Lymphadenitis/physiopathology , Lymphangitis/etiologyABSTRACT
Se comunica un caso de nocardiosis linfangítica en un paciente de sexo masculino de 53 años de edad, residente en Nogolí (Pcia. de San Luis), hachero, que presenta nódulos con disposición linfangítica en la pierna derecha y una lesión inicial en la cara interna del miembro inferior derecho de tipo úlcero-costrosa vegetante de bordes indurados y secreción purulenta, que clínicamente simulaba una esporotricosis. Los estudios micológicos y aislamiento del agente etiológico, sus características morfológicas y fisiológicas permiten fundamentar el hallazgo de Nocardia brasiliensis. El diagnóstico diferencial con otras patologías es de importancia y en especial con esporotricosis linfangítica gomosa, cuyo cuadro clínico es similar. El paciente fue tratado con la asociación trimetoprima-sulfametoxazol con lo que se obtuvo remisión del cuadro clínico
Subject(s)
Humans , Male , Middle Aged , Nocardia Infections/diagnosis , Nocardia/isolation & purification , Lymphangitis/etiology , Nocardia Infections/drug therapyABSTRACT
1. Experimental models of carcinomatous lymphangitis have not been described. This is an important clinical entity which usually results in the patients' death, although its natural history is still controversial. This study was undertaken to investigate whether the pattern of lung involvement after Walker 256 tumor inoculation through the trachea is a good model of carcinomatous lymphangitis. 2. Fifty male Wistar rats were inoculated through the trachea with 2.5 x 10(6) Walker 256 tumor cells and killed in groups of 5 animals each at 6 h and on days 1, 3, 7, 14, 21, 28, 35, 45, and 60 of the experiment. The lungs and thoracic lymph nodes were examined by light microscopy. 3. There were no tumors in the 25 animals killed before the 21st day of the experiment. The remaining 25 rats were sacrificed after 3 weeks of the experiment; 52 per cent of them displayed thoracic lymph node metastases, and 40 per cent developed a mild carcinomatous lymphangitis. The lung involvement did not correlate with respiratory distress, tumor dissemination or additional histological abnormalities. 4. We conclude that invasion of the lung is possible after intratracheal tumor cell inoculation, and that spreading follows a lymphatic pattern. This finding establishes this approach as a viable experimental model of carcinomatous lymphangitis. New approaches to increase the intensity and frequency of lung involvement, as well as the development of respiratory distress should be pursued in order to improve the efficiency of this model
Subject(s)
Animals , Male , Rats , Carcinoma 256, Walker/pathology , Lung Neoplasms/secondary , Lymphangitis/etiology , Lymphatic Metastasis , Neoplasm Transplantation , Rats, Wistar , Time FactorsSubject(s)
Humans , Histiocytosis , Histiocytosis/diagnosis , Histiocytosis/drug therapy , Histiocytosis/epidemiology , Histiocytosis/etiology , Histiocytosis/pathology , Histiocytosis/physiopathology , Histiocytosis/therapy , Lymphangitis/complications , Lymphangitis/etiology , Lung Diseases, Interstitial/classification , Lung Diseases, Interstitial/complications , Lung Diseases, Interstitial/diagnosis , Lung Diseases, Interstitial/epidemiology , Lung Diseases, Interstitial/etiology , Lung Diseases, Interstitial/physiopathology , Lung Diseases, Interstitial/pathology , Lung Diseases, Interstitial/drug therapy , Lung Diseases, Interstitial , Lung Diseases, Interstitial/therapyABSTRACT
Se considera que las lesiones del sistema linfático producidas en el curso de una safenectomía predispone a la aparición de linfangitis. Se estudiaron 50 pacientes que presentaban várices unilateral a los cuales se les realizó tratamiento quirúrgico, con el objeto de conocer el riesgo de padecer de linfangitis en función de la cirugía. Se concluye que es la insuficiencia venosa, que en la evolución se acompaña de edema, úlcera, etcétera, la que condiciona el terreno para que aparezca la linfangitis. Resultó significativa la frecuencia de que un paciente varicoso operado o no padezca de linfangitis por padecer de úlcera varicosa y/o epidermofitosis
Subject(s)
Humans , Male , Female , Lymphangitis/etiology , Varicose Veins/surgeryABSTRACT
Se presenta un caso de linfangitis crónica hipertrófica sobre linfangiectasia adquirida circunscripta. Se realiza una revisión bibliográfica sobre las diferentes causas y se establecen diagnósticos diferenciales clínicos e histológicos